If you are looking for the gallery, see Smith & Wesson 3913 "Ladysmith" Gallery.
S&W Model 3913

Andrea (Laurie Holden) carries a Smith & Wesson 3913 "Ladysmith" in Season 1 Episode 2, Guts. She later hands the pistol to Glenn (Steven Yeun) for his own protection when he and Rick make their way to the escape van, he does not fire it in the escape though. Andrea uses it in Season 1 Episode 5, Wildfire, to put her sister Amy down after she comes back as a walker. Shane Walsh briefly handles the Ladysmith in Season 2 Episode 1, What Lies Ahead, as he intends to teach Andrea how to take it apart and clean it but Dale keeps the gun from her fearing a suicide attempt until a couple episodes later in Season 2 Episode 3, Save the Last One, in which he returns it. Shane finally gets around to teaching Andrea how to break her gun down in the following episode Season 2 Episode 4, Cherokee Rose. Andrea fires it well during a target practice session in Season 2 Episode 6, Secrets, before switching to a Beretta by the recommendation of Shane. T-Dog (IronE Singleton) can be seen holding Andrea's Smith & Wesson 3913 "Ladysmith" while the group talk on the road in Season 2 Episode 13, Beside the Dying Fire, after escaping Hershel's farm.